Total Publications 75
h-Index 22
i10 44
Total citations 1249
Patent Published
Synthesis Of New Triazolyl Linked Bile Acid Aryl Ketones
IN Patent Application: 201911006301
Book Chapters
3. Transition Metal-Catalyzed C–H Functionalization of Imidazo-fused Heterocycles
Rajeev Sakhuja, Anil Kumar, Wiley, 2023, Vol. 2, Chapter 11 (ISBN: 978-1-119-77413-6).
2. C–H Functionalization of Indazoles
Anil Kumar, Rajeev Sakhuja, Handbook of C-H Functionalization, Wiley, 2022 (ISBN 9783527834242).
1. Benzotriazole: Much More Than Just Synthetic Heterocyclic Chemistry
K Bajaj, Rajeev Sakhuja, Topics in Heterocyclic Chemistry, Springer International Publishing Switzerland, 2016, 43.
Journal Publications
2023
75. Palladium-Catalyzed Regioselective C-Arylation and C,N-Diarylation of N-Aryl-2,3-dihydrophthalazine-1,4-diones Using Diaryliodonium SaltsNaharwal, S.; Kharat, N. D.; Mahesha, C. K.; Bajaj, K.; Sakhuja, Rajeev, Synthesis 2023, 55, A-K.
74. Tandem Transformations of Indazolones to Quinazolinones through Pd-catalyzed carbene Insertion into N-N bond
- Mahesha, C. K.; Borade, S. A.; Tank, D.; Bajaj, K.; Bhambri, H.; mandal, S. K.; Sakhuja, Rajeev, Journal of Organic Chemistry 2023, 88, 1457-1468.
2022
- Kharat, Narendra Dinkar; Mahesha, Chikkagundagal K.; Bajaj, Kiran; Sakhuja, Rajeev, Organic Letters 2022, 24, 6857-6862.
72. Ruthenium-catalyzed (spiro)annulation of N-aryl-2,3-dihydrophthalazine-1,4-diones with quinones to access pentacyclic spiro-indazolones and fused-cinnolines
Naharwal, S.; Karishma, P.; Mahesha, C. K.; Bajaj, K.; Mandal S. K.; Sakhuja, Rajeev, Organic & Biomolecular Chemistry, 2022, 20, 4753-4764.
71. Development
of Isatin-Based Schiff Bases Targeting VEGFR-2 Inhibition: Synthesis,
Characterization, Antiproliferative Properties, and QSAR Studies
Seliem,
I. A., Panda, S. S., Girgis, A. S., Tran, Q. L., Said, M. F.,
Bekheit, M. S., Abdelnaser, A., Nasr, S., Fayad, W., Soliman, A. A. F., Sakhuja, Rajeev, Ibrahim, T. S. ChemMedChem, 2022, 17(13), e202200164
70. Regiodivergent Synthesis of Cinnoline-fused Indazolones through Pd-catalyzed Annulation of 1-Arylindazolones with Allenoates
Mahesha, C. K.; Naharwal, S.; Dinkar, N. K.; Mandal, S. K.; Sakhuja, Rajeev, Journal of Organic Chemistry 2022, 87, 3701-3706.
69. Synthesis, Antibacterial Evaluation, and Computational Studies of a Diverse Set of Linezolid Conjugates
Bokhtia, R. M.; Girgis, A. S.; Ibrahim, T. S.; Rasslan, F.; Nossier, E. S.; Barghash R. F.; Sakhuja, Rajeev, Abdel-Aal, E. H.; Panda. S. S. Pharmaceuticals 2022, 15, 191-214.
2021
68. Rhodium-Catalyzed Spirocyclization of Maleimide with N-Aryl-2,3-dihydrophthalazine-1,4-dione to Access Pentacyclic Spiro-Succinimides
Karishma, P.; Mandal, S. K.; Sakhuja, Rajeev, Asian Journal of Organic Chemistry 2021, 10(10), 2580-2590.
67. Bile acid Appended Triazolyl Aryl Ketones: Design, Synthesis, in vitro Anticancer Activity and Pharmacokinetics in Rats
Agarwal, D. S.; Mazumdar, S.; Italiya, K. S.; Chitkara, D.; Sakhuja, Rajeev, Molecules 2021, 26(19), 5741.
66. Fluorescent glutamine and asparagine as promising probes for chemical biology
Bajaj, K.; Karishma, P.; Khan, S.; Jha, P. N.; Sakhuja, Rajeev; Kumar, D. Organic & Biomolecular Chemistry 2021, 19(35), 7695-7700.
65. New quinoline-triazole conjugates: Synthesis, and antiviral properties against SARS-CoV-2
Seliem, I. A.; Panda, S. S.; Girgis, A. S.; Moatasim, Y.; Kandeil, A.; Mostafa, A.; Ali, M. A.; Nossier, E. S.; Rasslan, F.; Srour, A. M.; Sakhuja, Rajeev, Bioorganic Chemistry 2021, 114, 105117.
64. Reducing-Agent-Free Convergent Synthesis of Hydroxyimino-Decorated Tetracyclic Fused Cinnolines via RhIII-Catalyzed Annulation Using Nitroolefins
Karishma, Pidiyara; Mahesha, Chikkagundagal K.; Mandal, Sanjay K.; Sakhuja, Rajeev, Journal of Organic Chemistry, 2021, 86(3), 2734-2747.
Karishma, Pidiyara; Gogia, Alisha; Mandal, Sanjay K.; Sakhuja, Rajeev, Advanced Synthesis & Catalysis 2021, 363(3), 762-775. |
Bokhtia, R. M; Panda S. S; Honkanadavar H. H; Girgis A. S; Ibrahim T. S; Al-Mahmoudy A. M M; Abdel-Aal E. H; George R. F; Kashef M. T; Fayad W.; Sakhuja, Rajeev Medicinal chemistry 2021, 17(1), 71-84. |
2020
61. Expansion of phosphane treasure box for staudinger peptide ligation 
|
60. Indazolone-Assisted Sequential ortho-Alkenylation-Oxidative Aza-Michael Addition of 1-Arylindazolone Using Acrylates Under Ru(II) Catalysis
|
Sharma, S.; Pukale, S. S.; Sahel, D. K.; Agarwal, D.; Manu, D.; Mohanty, S.; Sakhuja, Rajeev, Mittal, A., Chitkara, D. AAPS PharmSciTech, 2020, 21(7), 280. |
58. Fabrication of Deoxycholic Acid tethered α-Cyanostilbenes as Smart Low Molecular Weight Gelators and AIEE probes for Bio-imaging Agarwal, D.; Singh, R. P.; Jha, P. N.; Sakhuja, Rajeev, Steroids 2020 160, 108659. 
|
| 57. Design, synthesis, antimicrobial, and DNA gyrase inhibitory properties of fluoroquinolone-dichloroacetic acid hybrids Seliem, I. A.; Panda, S. S.; Girgis, A. S.; Nagy, Y. I.; George, R. F.; Fayad, W.; Fawzy, N. G.; Ibrahim, T. S.; Al-Mahmoudy, A. M. M.; Sakhuja, Rajeev. Chemical Biology & Drug Design 2020, 95, 248. |
2019
56. Ruthenium Catalyzed C-H Acylmethylation of N-Arylphthalazine-1,4-diones with α-Carbonyl Sulfoxonium Ylides: Highway to Diversely Functionalized Phthalazino-fused Cinnolines
Karishma, P.; Agarwal, D. S.; Laha, B.; Mandal, S. K.; Sakhuja, R. Chemistry-An Asian Journal 2019, 14, 4274.
55. NH4OAc-Promoted Cascade Approach towards Aberrant Synthesis of Chromene-Fused Quinolinones
Kumari, Santosh; Shakoor, S. M. Abdul; Markad, Datta; Mandal, Sanjay K.; Sakhuja, Rajeev, European Journal of Organic Chemistry 2019, 2019(4), 705.
2018
54. Iridium-catalyzed [4+2] annulation of 1-arylindazolones with α-diazo carbonyl compounds: access to indazolone-fused cinnolines
Mahesha, Chikkagundagal K.; Agarwal, Devesh S.; Karishma, Pidiyara; Markad, Datta; Mandal, Sanjay K. Sakhuja, Rajeev, Organic & Biomolecular Chemistry, 2018, 16(44), 8585.
3. 53. Clickable conjugates of bile acids and nucleosides: Synthesis, characterization, in vitro anticancer and antituberculosis studies
Agarwal, Devesh S.; Siva Krishna, Vagolu; Sriram, Dharmarajan; Yogeeswari, Perumal; Sakhuja, Rajeev, Steroids 2018, 139, 35.
4. 52. Additive-Driven Rhodium-Catalyzed [4+1]/[4+2] Annulations of N-Arylphthalazine-1,4-dione with α-Diazo Carbonyl Compounds
Karishma, Pidiyara; Mahesha, Chikkagundagal K.; Agarwal, Devesh S.; Mandal, Sanjay K.; Sakhuja, Rajeev, Journal of Organic Chemistry 2018, 83(19), 11661.
5. 51. Aziridine based electrophilic handle for aspartic acid ligation
Bajaj, Kiran; Agarwal, Devesh S.; Sakhuja, Rajeev; Pillai, Girinath G. Organic & Biomolecular Chemistry 2018, 16(23), 4311.
6. 50. An unprecedented tandem synthesis of fluorescent coumarin-fused pyrimidines via copper-catalyzed cross-dehydrogenative C(sp3)-N bond coupling
Kumari, Santosh; Abdul Shakoor, S. M.; Khullar, Sadhika; Mandal, Sanjay K.; Sakhuja, Rajeev, Organic & Biomolecular Chemistry 2018, 16(17), 3220.
7. 49. Synthesis and evaluation of bile acid amides of α-cyanostilbenes as anticancer agents
Agarwal, Devesh S.; Singh, Rajnish Prakash; Lohitesh, K.; Jha, Prabhat N.; Chowdhury, Rajdeep; Sakhuja, Rajeev Molecular Diversity 2018, 22(2), 305.
2017
48. Solvent-Driven Iodine-Mediated Oxidative Strategies for the
Synthesis of Bis(imidazo[1,2-a]pyridin-3-yl)sulfanes and Disulfanes
Shakoor, S. M.; Agarwal, D.; Khullar, S.; Mandal, S. K.; Sakhuja, Rajeev; Chemistry An Asian Journal, 2017, 23, 3061-3068.
47. Detection of Hg2+ ions in aqueous medium using an indole-based
fluorescent probe: Experimental and theoretical investigations
Joshi, S.; Kumari, S.; Sarmah, A.; Pant, D. D.; Sakhuja, Rajeev. Journal of Molecular Liquids, 2017, 248, 668-677.
46. Aziridine-Mediated Ligation at Phenylalanine and Tryptophan Sites
Bajaj, K.; Sakhuja, Rajeev; Chemistry An Asian Journal, 2017, 12, 1869-1874.
45. One-Pot Synthesis of Carbon Nanodots in an Organic Medium with Aggregation-Induced Emission Enhancement (AIEE): A Rationale for “Enzyme-Free” Detection of Cholesterol
Gogoi, N.; Agarwal, D.; Sehgal, A.; Chowdhury, D.; Sakhuja, Rajeev, ACS Omega, 2017, 2, 3816-3827.
Shakoor, S. M. A.; Mandal, S. K.; Sakhuja, Rajeev, European Journal of Organic Chemistry 2017, 18, 2596-2602.
43. Solvent effects on the absorption and emission spectra of novel (E)-4-((4-(heptyloxy)phenyl)diazenyl)benzyl (((9H-fluoren-9-yl) methoxy)carbonyl)-D-alaninate (Fmoc-al-az): Determination of dipole moment by experimental and theoretical study.
Varma, T.; Agarwal, D. S.; Sarmah, A. Joshi, L.; Sakhuja, Rajeev, Pant, D. D., Journal of Molecular Structure, 2017, 1129, 248.
2016
42. Ruthenium(II)-catalyzed regioselective ortho amidation of imidazo heterocycles with isocyanates
Shakoor, S. M. A.; Kumari, S.; Khullar, S.; Mandal, S. K.; Kumar, A.; Sakhuja, Rajeev, Journal of Organic Chemistry 2016, 81, 12340.
41. Highly Selective Sensing of Li+ in H2O/CH3CN via Fluorescence ‘Turn-on’ Response of a Coumarin-Indole Linked Dyad: an Experimental and Theoretical Study
Kumari, S.; Joshi, S.; Sarmah, A.; Pant, D. D.; Sakhuja, Rajeev. Journal of Fluorescence 2016, 26, 2177.
40. Traceless reductive ligation at a tryptophan site: a facile access to β-hydroxytryptophan appended peptides
Bajaj, K.; Sakhuja, Rajeev; Pillai G. Org. Biomol. Chem. 2016, 14, 9578.
39. Amino Acid Appended Cholic acid-Azobenzene Dyad: An Effective & Smart Phase selective Gelator for Aromatic solvents
Agarwal, D. S.; Gogoi, N.; Chowdhury, D.; Sakhuja, Rajeev RSC Advances 2016, 6, 76632.
38. Experimental and Quantum Chemical Calculations of Imidazolium Appended Naphthalene Hybrid: In Different Bio-Mimicking Aqueous Interfaces
Yenupuri, T. V.; Mydlova, L.; Agarwal, D. S.; Sharma, R.; Sakhuja, Rajeev; Makowska-Janusik, M; Pant, D. D.J. Phys. Chem. A, 2016, 120, 6563.
37. Ytterbium triflate catalyzed synthesis of heterocycles
Sakhuja Rajeev ; Pericherla, K.; Bajaj, K.; Khungar, B.; Kumar. A. Synthesis 2016, 48, 4305.
36. Synthesis, characterization and biological evaluation of bile acidaromatic/ heteroaromatic amides linked via amino acids as anti-cancer agents
Agarwal, D. S.; Anantaraju, H. S.; Sriram, D.; Yogeeswari, P.; Nanjegowda, S. H.; Mallu, P. Sakhuja, Rajeev. Steroids 2016, 107, 87.
35. Copper catalyzed direct aerobic double-oxidative crossdehydrogenative coupling of imidazoheterocycles with aryl acetaldehydes: an articulate approach for dicarbonylation at C-3 Position
Shakoor, S. M. A.; Agarwal, D. S.; Kumar, A.; Sakhuja, Rajeev. Tetrahedron 2016, 72, 645.
34. Copper-catalysed C-N/C-O coupling in water: a facile access to N-coumaryl amino acids and fluorescent tyrosine & lysine labels
Kumari, S.; Shakoor, S. M. A.; Bajaj, K.; Nanjegowda, S. H.; Mallu, P.; Sakhuja, Rajeev Tetrahedron Letters 2016, 57, 2732
33. Design and synthesis of amino acid appended azo dye hybrid: Characterization, solvatochromic and quantum-chemical calculations using experimental and theoretical approach
Varma Y, T.; Agarwal, D. S.; Sarmah, A.; Yukti; Sakhuja, Rajeev; Pant, D. D. Journal of Molecular Liquids 2016, 221, 1022.
32. Solvatochromic shift and estimation of dipole moment of synthesized coumarin derivative: Application as sensor for fluorogenic recognition of Fe3+ and Cu2+ ions in aqueous solution
Joshi, S.; Kumari, S.; Sarmah, A.; Sakhuja, Rajeev; Pant, D. D. Journal of Molecular Liquids 2016, 222, 253.
31. Highly sensitive fluorescent imidazolium-based sensors for nanomolar detection of explosive picric acid in aqueous medium
Kumari, S. Joshi, S.; Cordova-Sintjagoc, T. C.Pant, D. D.; Sakhuja, Rajeev. Sensors and Actuators B 2016, 229, 599.
30. Fluorescence Quenching of a Benzimidazolium–based Probe for Selective Detection of Picric Acid in Aqueous Medium
Joshi, S; Kumari, S.; Chamorro, E.; Pant, D. D.; Sakhuja. Rajeev, ChemistrySelect 2016, 1, 1756.
2015
29. Experimental and theoretical study: Determination of dipole moment of synthesized coumarin–triazole derivatives and application as turnoff fluorescence sensor: High sensitivity for iron(III) ions
Joshi, S.; Kumari, S.; Bhattacharjee, R.;Sarmah, A.; Sakhuja,Rajeev, Pant, D. D. Sensors and Actuators B 2015, 220, 1266.
28. Estimation of ground and excited-state dipole moments of synthesized coumarin derivative, (S)-(1-((7-hydroxy-2-oxo-2H-chromen-4-yl) methyl)-1H-1,2,3-triazol-4-yl)methyl 2-(((9H-fluoren-9-yl)methoxy) cabonylamino)-3-phenylpropanoate from a solvatochromic shift and theoretical methods
Joshi, S.; Kumari, S.; Bhattacharjee, R.; Sakhuja, Rajeev; Pant, D. D. Journal of Molecular Liquids 2015, 209, 219.
27. Imidazolium-supported benzotriazole: An efficient and recoverable activating reagent for amide, ester and thioester bond formation in water
Shakoor, S. M. Abdul; Choudhary, S.; Bajaj, K.; Muthyala, M. K.; Kumar, A.; Sakhuja Rajeev. RSC Adv., 2015, 5, 82199.
26. Novel 4-substituted-N,N-dimethyltetrahydronaphthalen-2-amines: synthesis, affinity, and in silico docking studies at serotonin 5-HT2-type and histamine H1 G protein-coupled receptors
Sakhuja, Rajeev; Kondabolu, K.; Córdova-Sintjago, T.; Travers, S.; Vincek, A. S. Kim, M. S. Abboud, K. A.; Fang, L.; Sun, Z.; Canal, C. E.; Booth, R. G. Bioorganic & Medicinal Chemistry 2015, 23, 1588.
25. Synthesis, Absorption, and Fluorescence Studies of Coumaryl-Labelled Amino Acids and Dipeptides Linked Via Triazole Ring
Kumari, Santosh, Joshi, S., Shakoor, S. M. A., Agarwal, D. S., Panda, S. S., Pant, D. D., Sakhuja, Rajeev. Australian Journal of Chemistry 2015, 68, 1415.
24. Microwave-assisted Expedite Synthesis of 2-Phenylimidazo[1,2-a]pyridyl quinoxalin-2(1H)-ones
Sakhuja, Rajeev; Shakoor, S. M. A.; Kumari, S.; Kumar, A. Journal of Heterocyclic Chemistry 2015, 52(30), 773.
2014
23. Microwave-assisted Synthesis of Benzo-fused Seven-membered Azaheterocycles
Sakhuja, Rajeev; Bajaj, K.; Shakoor, S. M. A.; Kumar, A. Mini Review in Organic Chemistry 2014, 11(1), 55.
22. Estimation of ground and excited state dipole moments of synthesized coumarin derivative [N-(2-oxo-2H-chromen-4-yl)imino] triphenyl-phosphorane
Joshi, S.; Kumari, S.; Bhattacharjee, R.; Sakhuja, Rajeev; Pant, D. D. Journal of Molecular Liquids 2014, 200, 115.
21. Phytochemical Investigation of Tabebuia palmeri
Sakhuja, Rajeev; Vashist, M; Bhoon, Y. K.; Jain, S. C. Chemistry of Natural Compounds 2014, 49, 1039.
2013
20. Xanthones as Potential Antioxidants
Sakhuja, Rajeev; Jain, S. C. Current Medicinal Chemistry 2013, 20, 4481.
Panda, S. S.; Chand, M.;
19. Molecular and behavioral pharmacology of two novel orally-active 5HT2 modulators:Potential utility as antipsychotic medications
Morgan, D.; Kondabolu, K; Kuipers, A.; Sakhuja, Rajeev; Robertson, K. L.; Rowland, N. E.; Booth, R. G. Neuropharmacology 2013, 72, 274.
18. Synthesis and antimicrobial activity of novel bis-azaphenothiazines
Kushwaha, K.; Sakhuja, Rajeev; Jain, S. C. Medicinal Chemistry Research 2013, 22(9),4459.
2012 & earlier
17. Molecular determinants for ligand binding at serotonin 5-HT2A and 5-HT2C GPCRs: Experimental affinity results analyzed by molecular modeling and ligand docking studies
Córdova-Sintjago, T.; Sakhuja, Rajeev; Kondabolu, K.; Canal, C. E.; Booth, R.G. International Journal of Quantum Chemistry 2012, 112, 3807.
16. N-Hydroxyamidoxime, N-aminoamidoximes and hydrazidine
Katritzky, A. R.;Huang, L.; Chahar M. ; Sakhuja, Rajeev; Hall, C. D. Chemical Review 2012, 112, 1163.
15. Microwave assisted synthesis of five membered azaheterocyclic systems
Sakhuja, Rajeev; Panda, S. S.; Bajaj, K. Current Organic Chemistry 2012, 16, 789.
14. Design and synthesis of spiro[indole-thiazolidine]spiro[indole-pyrans] as antimicrobial agents
Sakhuja, Rajeev, Panda, S. S., khanna, L., Khurana, S., Jain, S. C. Bioorganic & Medicinal Chemistry Letters2011, 21(8), 5465.
13. Carbene mediated transformations of 1-(benzylideneamino)benzimidazoles
Katritzky, A. R.; Jishkariani, D.; Sakhuja, Rajeev; Hall, C. D.; Steel, P. Journal of Organic Chemistry 2011, 76(10), 4082.
12. Microwave-assisted synthesis of azoniaspiro compounds using a novel catalyst, 1-azaphenothiazine
Gupta, A.; Sakhuja, Rajeev; Kushwaha, K.; Jain, Subhash C. Synthetic Communications2011, 41(3), 411.
11. Efficient syntheses of naphthoquinone-dipeptides
Katritzky, A. R.; Huang, L.; Sakhuja, Rajeev Synthesis 2010, (12), 2011.
10. Effect of filler loading on the mechanical properties of crosslinked 1,2,3-triazole polymers
Katritzky, A. R.; Sakhuja, Rajeev; Huang, L.; Gyanda, R.; Wang, L.; Jackson, D. C.; Ciaramitaro, D. A.; Bedford, C. D.; Duran, R. S. Journal of Applied Polymer Science 2010, 118(1), 121.
9. Preparation and mechanical properties of crosslinked 1,2,3-triazole-polymers as potential propellant binders
Wang, L.; Song, Y.; Gyanda, R.; Sakhuja, Rajeev; Meher, N. K.; Hanci, S.; Gyanda, K.; Mathai, S.; Sabri, F.; Ciaramitaro, D. A.; Katritzky, A. R. Journal of Applied Polymer Science 2010, 117(5), 2612.
8. Effect of the crosslink functionality on the mechanical properties of crosslinked 1,2,3-triazole polymers as potential binders for rocket propellants
Song, Y.; Wang, L.; Gyanda, R.; Sakhuja, Rajeev; Cavallaro, M.; Jackson, D. C.; Meher, N. K.; Ciaramitaro, D. A.; Bedford, C. D.; Katritzky, A. R. Journal of Applied Polymer Science 2010, 117(1), 473.
7. Synthesis of Boltorn 1,2,3-triazole dendrimers by click chemistry
Katritzky, A. R.; Song, Y.; Sakhuja, Rajeev; Gyanda, R.; Meher, N. K.; Wang, L.; Duran, R. S.; Ciaramitaro, D. A.; Bedford, C. D. Journal of Polymer Science, Part A: Polymer Chemistry 2009, 47(15), 3748.
6. Gelation behavior of 2H-chromene N-acylamino acid conjugates
Katritzky, A. R.; Sakhuja, Rajeev; Khelashvili, L.; Shanab, K. Journal of Organic Chemistry 2009, 74(8), 3062.
5. A facile synthesis of novel unsymmetrical bis-spiro[indole-pyrazolinyl-thiazolidine]-2,4'-diones
Jain, M.; Sakhuja, Rajeev; Khanna, P.; Bhagat, S.; Jain, S. C., Arkivoc, 2008, 15, 54.
4. Microwave assisted synthesis of 10-(phthalimidoalkyl)-halosubstitutedpyrido[3,2-b][1,4]-benzothiazine in dry media
Gupta, A.; Sakhuja, Rajeev; Jain S. C., Synthetic Communication, 2007, 37(22), 4059.
3. Novel fluorinated spiro[indole-indazolyl-thiazolidine]-2,4¢-diones: Design and synthesis
Jain, S. C.; Khanna, P.; Bhagat, S.; Jain, M.; Sakhuja, Rajeev, Phosphorus, Sulfur Silicon and their Related Elements, 2005, 180(8), 1829.
2. A new flavone-glycoside from Zanthoxylum acanthopodium DC
Babu, B. R.; Khurana, S.; Sakhuja, Rajeev; Srivastava, A. K.; Jain, S. C., Indian J Chem., 2007, 46B, 842.
1. Lewis acid promoted synthesis of 2(3H)-benzofuranones
Babu, B. R.; Bali, S.; Sakhuja, Rajeev; Jain, S. C., Indian J Chem. 2006, 45B, 2546.